Primary Outcomes and Morbi-mortality Associated Factors in the Coronary Angioplasty

Alejandro Cherro, Carlos Fernández Pereira, Ernesto Torresani, Daniel O. Mauro, Carlos A. Ingino, José A.G. Alvarez, Raúl A. Borracci, Jorge G. Allin, Miguel A. Miceli, Ricardo A. Sarmiento



Percutaneous transluminal coronary angioplasty (PTCA) outcomes were compiled in the 1996 CONAREC V Registry, and in 2005, data collection was repeated using a similar methodology, giving rise to the CONAREC XIV Registry. As no general national PTCA results have been reported since, the Argentine Society of Cardiology, together with CACI, FAC and CONAREC carried out the Coronary Angioplasty Argentine Registry (RAdAC).


The aim of this Registry was to evaluate in-hospital outcome and morbi-mortality of patients submitted to PTCA according to different clinical scenarios.


One thousand nine hundred and five patients were prospectively and consecutively included in 67 centers of Argentina during a 7-month period. Cardiovascular risk factors and clinical history were analyzed. PTCA procedures were classified as: planned, urgent or emergent and the number of affected and intended-to-treat vessels, as well as the number and type of stents implanted [bare metal (BMS) or drug eluting stents (DES)] were estimated. Use of atherectomy, Cutting BalloonÒ, thrombus aspiration, intravascular ultrasound (IVUS), antiplatelet drugs and intra-aortic balloon pump (IABP) was analyzed. Angiographic success was defined as residual lesion <20% and normal flow (TIMI 3).


Mean age was 63.8 years. A total of 752 patients (39.5%) presented with acute myocardial infarction (AMI) and 834 patients (43.8%) unstable angina (UA). Femoral access was used in 92.8% of the cases. Overall, 44.3% of the interventions were planned, 37.8% were urgent and 17.9% emergent. A total of 2753 stents were implanted (1.4 per patient), 33.2% of which were DES. The primary success rate was 97% and overall mortality 1.6%: 3.2% associated to AMI, (4.3% STEMI and 1.7% non-STEMI), 0.8% to UA and 0.3% to chronic stable angina. Death-associated variables were: cardiogenic shock, requirement of IAPB, Killip-Kimball 3-4, emergency PTCA, left main PTCA, ventricular function impairment, renal failure or diabetes, number of affected vessels, age and PTCA failure.


In our setting, most PTCAs are performed in acute coronary syndromes, almost exclusively by femoral access, with primary success comparable to that of international reports, but using less DES. Use of RotablatorÒ, Cutting BalloonÒ, thrombus aspiration, IVUS and IABP implementation was lower than expected, while age, cardiogenic shock, emergency and PTCA failure were factors associated with increased morbi-mortality.

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Revista argentina de cardiología. ISSN en línea 1850-3748. Argentine journal of cardiology (English ed. Online ISSN 2314-2286) Sociedad Argentina de Cardiología. Azcuénaga 980 (C1115AAD),Ciudad Autónoma de Buenos Aires, República Argentina. Tel. (54 11) 4961-6027/8/9 Fax: 4961-6020