Long-QT Syndrome Secondary to Hypocalcemia

Juan Jiménez-Jaimez, Ricardo Sebastián Galdeano, Isabel Almansa Valencia, Miguel Álvarez López, Luis Tercedor Sánchez

Abstract


Long-QT syndrome is a congenital or acquired disorder that

produces sudden death due to ventricular arrhythmias. Electrolyte disturbances and medications are the most common causes of acquired long-QT syndrome. We describe the case of a patient with long-QT syndrome secondary to hypocalcemia caused by primary hypoparathyroidism. The secondary causes of long-QT syndrome should be thoroughly examined as they are more common than the genetic causes. Also, as they are reversible with adequate etiological treatment, their correct identification avoids unnecessary diagnostic and therapeutic measures.


References


Huang TC, Cecchin FC, Mahoney P, Portman MA. Corrected QT

interval (QTc) prolongation and syncope associated with pseudohypoparathyroidism

and hypocalcemia. J Pediatr 2000;136:404-7.

Eryol NK, Colak R, Ozdoğru I, Tanriverdi F, Unal S, Topsakal R,

Katlandur H, Bayram F. Effects of calcium treatment on QT interval

and QT dispersion in hypocalcemia. Am J Cardiol 2003;91:750-2.

Zhang L, Timothy KW, Vincent GM, Lehmann MH, Fox J, Giuli LC,

et al. Spectrum of ST-T-wave patterns and repolarization parameters

in congenital long-QT syndrome: ECG findings identify genotypes.

Circulation 2000;102:2849-55.

Priori SG, Schwartz PJ, Napolitano C, Bloise R, Ronchetti E, Grillo

M,Vicentini A, Spazzolini C, Nastoli J, Bottelli G, Folli R, Cappelletti

D. Risk stratification in the long-QT syndrome. N Engl J Med

;348:1866-74.

Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ,

Priori SG, Roden DM, George AL Jr, Goldstein SA. A common polymorphism

associated with antibiotic-induced cardiac arrhythmia.

Proc Natl Acad Sci U S A 2000;97:10613-8.

Gordon E, Panaghie G, Deng L, Bee KJ, Roepke TK, Krogh-

Madsen T, Christini DJ, Ostrer H, Basson CT, Chung W, Abbott GW.

A KCNE2 mutation in a patient with cardiac arrhythmia induced by

auditory stimuli and serum electrolyte imbalance. Cardiovasc Res

;77:98-106.

Buber J, Goldenberg S, Eyal A, Mouallem M, Farfel Z. Hypocalcemia,

prolonged QT interval and massive brain calcifications in an Iranian

Jewish woman with APECED. Isr Med Assoc J 2008;10:899-900.


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Revista argentina de cardiología. ISSN en línea 1850-3748. Argentine journal of cardiology (English ed. Online ISSN 2314-2286) Sociedad Argentina de Cardiología. Azcuénaga 980 (C1115AAD),Ciudad Autónoma de Buenos Aires, República Argentina. Tel. (54 11) 4961-6027/8/9 Fax: 4961-6020 www.sac.org.ar revista@sac.org.ar