Non-Compaction Cardiomyopathy. Risk Stratification of Sudden Death for Automatic Cardioverter Defibrillator Implantation

Néstor O. Galizio, José L. González, Liliana E. Favaloro, Mirta Diez, Adrián Fernández, Eduardo Guevara, Alejandro A. Palazzo, Federico Robles, José H. Casabé



Non-compaction cardiomyopathy is a rare disease. Its natural history includes heart failure, thromboembolic events, arrhythmias and sudden death (SD). In the absence of data from randomized studies or records, the ACC / AHA / HRS 2008 guidelines recommend the automatic implantable cardioverter defibrillator (AICD) in all patients with non-compaction cardiomyopathy to reduce the risk of suden death.


Describe the outcomes of patients with non-compaction cardiomyopathy according to selected criteria for risk stratification of sudden death to decide the implantation of an AICD.

Material and Methods

A total of 80 patients were analyzed. The diagnosis was established by echocardiography and nuclear cardiac magnetic resonance imaging criteria.

The criteria for implantation of an AICD as a secondary prevention included sudden death and sustained ventricular tachycardia (SVT); as primary prevention included left ventricular ejection fraction (LVEF) < 30% or ≥ 2 risk factors (family history of sudden death [FHSD], syncope and non-sustained VT).





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Revista argentina de cardiología. ISSN en línea 1850-3748. Argentine journal of cardiology (English ed. Online ISSN 2314-2286) Sociedad Argentina de Cardiología. Azcuénaga 980 (C1115AAD),Ciudad Autónoma de Buenos Aires, República Argentina. Tel. (54 11) 4961-6027/8/9 Fax: 4961-6020